Routes · Americas
San Francisco to Argentina: Mendoza and Bariloche
San Francisco → Mendoza → Bariloche
Malbec vineyards & Patagonian lakes Best season (general guide): Nov–Apr
Argentina's Andes are home to two very different regions: the dry vineyards of Mendoza and the lakes and forests of northern Patagonia. This route spends three nights in Mendoza and four in Bariloche. From San Francisco you'll connect through a US hub and Buenos Aires or Santiago.
How to pace it: Spend days one to three in Mendoza: day one, Plaza Independencia; day two, Luján de Cuyo wineries; day three, Uco Valley or Aconcagua viewpoint. Then spend days four to seven in Bariloche: day four, fly to Bariloche; day five, Circuito Chico and Cerro Campanario; day six, lake boat trip; day seven, hike in Nahuel Huapi.
Mendoza is the heart of Argentine wine, and Malbec is its signature grape. Wineries in Luján de Cuyo and the higher Uco Valley offer tours and tastings with the Andes behind the vines. A drive west towards the border passes viewpoints for Aconcagua, the highest mountain outside Asia.
A flight takes you south to Bariloche, on the shore of Nahuel Huapi Lake. The town is known for its chalet-style buildings and its chocolate shops.
Nahuel Huapi National Park surrounds the town. The Circuito Chico is a short scenic loop around lakes and forests, and a chairlift up Cerro Campanario gives one of the best views of the region. Boat trips cross the lake to islands and forests, and many trails lead into the mountains.
November to April is the best time for both regions. The grape harvest in Mendoza runs in late summer and early autumn.
In Mendoza, tree-lined streets have irrigation channels running beside them, and plazas fill with families in the evening. In Bariloche, trout and lamb are local specialities, and chocolate shops line the main street. Both towns are good bases for cycling, and bikes can be hired easily.
Good to know: In Mendoza, book winery tours ahead and consider a driver rather than driving yourself. Bariloche is busy in January, so book accommodation early.
Pack layers for cool lake evenings.
Suggested outline
San Francisco
Mendoza
Wineries in Luján de Cuyo and the Uco Valley, with the Andes and Aconcagua nearby.
"Vineyards below the Andes.jpg" by Beatrice Murch, CC BY-SA 2.0, via Wikimedia Commons· licence Bariloche
Lakes and forests of Nahuel Huapi, the Circuito Chico and chocolate shops.
Day by day
- Day 1 · Mendoza — Arrive; Plaza Independencia· San Francisco → Mendoza (by air) — long-haul; may arrive the next calendar day
- Day 2 · Mendoza — Luján de Cuyo wineries
- Day 3 · Mendoza — Uco Valley or Aconcagua viewpoint
- Day 4 · Bariloche — Fly to Bariloche· Mendoza → Bariloche (by air)
- Day 5 · Bariloche — Circuito Chico and Cerro Campanario
- Day 6 · Bariloche — Lake boat trip
- Day 7 · Bariloche — Hike in Nahuel Huapi
- Day 8 · Bariloche — Travel home from Bariloche· Bariloche → San Francisco (by air)
A suggested pace only; expedition days are set by the operator.
Flights, leg by leg
Each button opens a live, dated search. We don't show stored fares here: check today's price on the booking site.
- San Francisco → Mendoza (SFO → MDZ) · Check today's price Search fares SFO → MDZ · 3 Dec ↗
- Mendoza → Bariloche (MDZ → BRC) · Check today's price Search fares MDZ → BRC · 6 Dec ↗
Showing dates about a month ahead — change them when you search.
Mendoza
Plan the trip: Mendoza
- Airport transfer Airport transfers in Argentina on Kiwitaxi ↗
- Car hire Car hire in Mendoza on Localrent ↗
- eSIM eSIM data for Argentina on Airalo ↗
- Private transfer Private transfers in Mendoza on GetTransfer ↗
- Audio guide Self-guided audio tours on WeGoTrip ↗
- Travel insurance Travel insurance on EKTA ↗
- Flight delayed? Check flight delay compensation on AirHelp ↗
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Bariloche
More about San Carlos de Bariloche →
Plan the trip: San Carlos de Bariloche
- Airport transfer Airport transfers in Argentina on Kiwitaxi ↗
- Car hire Car hire in San Carlos de Bariloche on Localrent ↗
- eSIM eSIM data for Argentina on Airalo ↗
- Private transfer Private transfers in San Carlos de Bariloche on GetTransfer ↗
- Audio guide Self-guided audio tours on WeGoTrip ↗
- Travel insurance Travel insurance on EKTA ↗
- Flight delayed? Check flight delay compensation on AirHelp ↗
These links go to partner sites. We may earn a commission if you buy through them, at no extra cost to you. Prices and terms are set by the partner.
Partner links may earn LarkTours a commission at no extra cost to you. Prices, availability and terms are set by each partner.